The aim of the call "European Research Projects on Rare Diseases driven by Young Investigators" is to provide to young, independent investigators the opportunity of building transnational collaborations in the field of rare disease research. The transnational project should be based on complementarities and sharing of expertise, demonstrating a clear added value of the cooperation and impact of the expected results on patients affected by rare diseases. Eligible under this call will be young investigators who have been awarded their first PhD/MD or equivalent of doctoral degree since at least 2 and up to 10 years.